- The Mega Core is the target building on Mega Crab stages similar to the Headquarters on a normal base or the Power Core on an Operation base. This means that if the Mega Core is destroyed, any Buildings left on the base will blow up and you will have beaten the stage.
- The Mega Core is only found on Mega Crab stages during the Mega Crab event.
- The Headquarters Damage Rules apply to the Mega Core as well.
- It takes up a 7 by 7 square space which makes it too big to cover with one Smoke Screen or Medkit. As such, Smokey Warrior Rush strategies are not recommended for use against a Mega Core.